Changes in fertility and sexual function in survivors after chemotherapy for haematological malignancy and their partners
Sexual dysfunction is a common problem in the general population. About 40-45% of adult women and 20-30% of adult men have at least one manifest sexual dysfunction. By the increasing number of references regarding sexuality after cancer we are aware of the negative impact that cancer and the treatment can have on fertility and sexual functioning. Besides the physical impact of cancer diagnosis and treatment on fertility and sexuality, many studies also reported that cancer may have a negative effect on spousal relationship. The sexual partner/ spouse may also suffer from sexual problems. However, detailed information on fertility and sexual function in patients after chemotherapy for haematological malignancy is lacking. So far, only two prospective studies contributed to the understanding of sexual dysfunction after the treatment of haematological malignancies. This lack of knowledge hampers professionals to adequately inform and support patients on fertility and sexuality. It is therefore important to obtain more information on changes in fertility and sexual function in patients and their sexual partners.
1. To describe changes in fertility and sexual function in survivors and their sexual partners during 5 years after chemotherapy for hematological malignancy.
2. To obtain insight into the impact of sexual functioning on quality of life during 5 years after chemotherapy for hematological malignancy.
3. To evaluate the need for information of the adult survivor and their partners with regard to fertility and sexuality.
This is a longitudinal prospective multicenter study among 4 Dutch centers using patient reported outcome on fertility and sexuality. The questionnaires that we use are the International Index of Erectile Function (IIEF), the Female Sexual Function Index (FSFI). Quality of life is measured by the European Organisation for Research and Treatment of Cancer-Quality of life Questionnaire-C30 (EORTC QLQ-C30). We have developed a study specific questionnaire on need for information.
The results are not yet available.
This project is approved by the Medical Ethical Committee VUmc.
VU University Medical Center (VUmc), dpt. of Haematology (2010-2015).
C. Eeltink, RN MA, Clinical Nurse Specialist, dpt. of Hematology, VUmc.
Prof P. Huijgens, PhD MD, Internist-Hematologist, dpt. of Hematology, VUmc
Prof I.M. Verdonck-de Leeuw, PhD, Psychologist, Speech & Language Therapist, Linguïst, dpt. of Clinical Psychology, VU Faculty of Psychology and Education
J.A.J. Rood, MSc, Internist physician in training, PhD student, dpt. of Internal Medicine, VUmc
L. Incrocci, MD PhD, Radio Therapist, Sexologist, dpt of Radiation Oncology, Erasmus MC-Daniel den Hoed Cancer Center
C.J. Gamel, MD, Nurse, Teacher, Researcher, Division of Nursing Science, University Medical Centre Utrecht.
O. Visser, MSc, Internist-Hematologist, dpt. of Hematology, VUmc.
For questions, please contact:
Corien Eeltink, RN MA, Clinical Nurse Specialist
Phone: +31 (0)20-4443215