Effectiveness of voice quality in patients with early glottic carcinoma
Patients treated for early glottic carcinoma often have voice problems after treatment. To enable valid assessment in clinical practice and research projects, a 5-item screening questionnaire was designed for detection of voice impairment and the Voice Handicap Index (VHI) was translated and validated.
A randomised controlled trial was carried out to assess the efficacy of voice therapy in patients with voice problems after treatment for early glottic cancer. Of 177 patients, 6 to 120 months after treatment of early glottic cancer, 70 patients (40%) suffered from voice impairment based on the 5-item screening questionnaire. About 60% of these 70 patients were not interested in participating in the study. Twenty-three patients, willing to participate, were randomly assigned to a voice therapy group (n=12) or a control group (n=11). Multidimensional voice analysis (VHI), acoustic and perceptual voice quality analysis, videolaryngostroboscopy, and Voice Range Profile (VRP)) was conducted twice: before and after voice therapy or with 3 months in between for the controls.
Statistical analysis of the difference scores (post- minus pre-measurement), showed significant voice improvement after voice therapy on the total VHI-score, percent jitter and noise to harmonics ratio in the voice signal and on the perceptual rating of vocal fry.
Voice therapy proved to be effective in patients with voice problems after treatment of early glottic cancer. Improvement was not only noticed by the patients (VHI) but was also confirmed by objective voice parameters.
VUmc, dept of Otolayrngology - Head & Neck Surgery and Council of Health Care Assurance Companies.
drs. Christine D.L. van Gogh, ENT-specialist, researcher, dpt. Otolaryngology-Head&Neck Surgery, VUmc.
Prof I.M. Verdonck-de Leeuw, PhD, Psychologist, Speech and Language Therapist, Linguïst, dpt. Otolaryngology-Head&Neck Surgery, VUmc.
Prof H.F. Mahieu, PhD MD, ENT-specialist, dpt. Otolaryngology, Oncology, Meander Medical Center
For questions, please contact:
Christine D.L. van Gogh, MD, ENT-specialist
Phone: + 31 (0)204443690